SCHEMBL29401258

SCHEMBL29401258

O=C(NCCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.66
MDM2 Q00987 6/20 0.55
MDM4 O15151 1/20 0.54
TP53 P04637 1/20 0.54
TLR2 O60603 2/20 0.54
FOLH1 Q04609 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29528567 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL260631 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL178698 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29359997 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL178733 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29423590 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29401604 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119708 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL18148920 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119709 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3603648-B1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID SHIONOGI & CO (JP) 2025-09-17 EP disclosed
US-20250108124-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS BIOHAVEN THERAPEUTICS LTD (US) 2025-04-03 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4340859-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS Biohaven Therapeutics Ltd. (US) 2024-03-27 EP disclosed
CN-117412761-A Antibody drug conjugates for delivery of cytotoxic agents using MATE technology 拜奥海芬治疗学有限公司 2024-01-16 CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
US-20230173086-A1 PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES EAGLE RESOLUTE INVESTMENT LLC 2023-06-08 US disclosed
WO-2023090935-A1 METHOD FOR PRODUCING AGM PEPTIDES THAT BIND SPECIFICALLY TO NUCLEOLIN 애니젠 주식회사 2023-05-25 WO disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid SHIONOGI & CO., LTD. (JP) 2023-05-02 US disclosed
WO-2023069502-A2 PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES RESOLUTE BIO, INC. (US) 2023-04-27 WO disclosed
US-20230102309-A1 TYROSINE KINASE INHIBITOR CONJUGATES Ascendis Pharma Oncology Division A/S (DE) 2023-03-30 US disclosed
US-20230065814-A1 CONJUGATES OF-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS ASCENDIS PHARMA A/S (DK) 2023-03-02 US disclosed
WO-2022246086-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS BIOHAVEN THERAPEUTICS LTD. (US) 2022-11-24 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
EP-3986477-A1 CONJUGATES OF pi-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS Ascendis Pharma A/S (DK) 2022-04-27 EP disclosed
EP-3986478-A1 TYROSINE KINASE INHIBITOR CONJUGATES Ascendis Pharma Oncology Division A/S (DK) 2022-04-27 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid FABP1, POLRMT, SREBF1 KMT2A 1076/4885MDM2 3352/4885MDM4 2238/4885
US-20250108124-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS CD47, DOCK2, DOCK5 KMT2A 465/4885MDM2 1398/4885MDM4 560/4885
US-20230102309-A1 TYROSINE KINASE INHIBITOR CONJUGATES ABL1, ERBB2, ROS1 KMT2A 157/4885MDM2 403/4885MDM4 2584/4885
US-20230065814-A1 CONJUGATES OF-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS NQO1, NCL, ABCB1 KMT2A 2443/4885MDM2 424/4885MDM4 811/4885
US-20230173086-A1 PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES VIP, DNPEP, CD74 KMT2A 3576/4885MDM2 2022/4885MDM4 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.