Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351430 | 0.82 | PTGIR (0.45) | PTGDR2KDM4EALDH1A1MEN1GAA | |
| SCHEMBL8352068 | 0.79 | PTGIR (0.44) | PTGDR2KDM4EALDH1A1MEN1GAA | |
| SCHEMBL8354897 | 0.79 | ALDH1A1 (0.42) | PTGDR2PTGDRKDM4EALDH1A1MEN1 | |
| SCHEMBL8358363 | 0.78 | PTGIR (0.43) | PTGDR2KDM4EALDH1A1MEN1GAA | |
| SCHEMBL8965332 | 0.77 | PTGDR2 (0.69) | PTGDR2PTGDR | |
| SCHEMBL8358385 | 0.77 | ALDH1A1 (0.42) | PTGDR2PTGDRKDM4EALDH1A1MEN1 | |
| SCHEMBL8354870 | 0.76 | PTGDR2 (0.41) | PTGDR2PTGDR | |
| SCHEMBL8350938 | 0.75 | PTGIR (0.46) | PTGDR2KDM4EALDH1A1MEN1GAA | |
| SCHEMBL8350737 | 0.74 | PTGDR2 (0.39) | PTGDR2PTGDRALDH1A1MEN1GAA | |
| SCHEMBL8420559 | 0.72 | KCNA3 (0.61) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |