Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23868211 | 0.72 | SMN1; SMN2 (0.59) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8353884 | 0.72 | HSD17B10 (0.31) | TDP1HSD17B10 | |
| SCHEMBL12464850 | 0.71 | HSD17B10 (0.31) | TDP1HSD17B10 | |
| SCHEMBL4977210 | 0.70 | ALDH1A1 (0.38) | LMNATDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL4980808 | 0.69 | HRH1 (0.42) | LMNATDP1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL13349704 | 0.67 | PTPRA (0.43) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4977212 | 0.67 | L3MBTL1 (0.38) | LMNATDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL13349692 | 0.66 | PTPRA (0.42) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12564742 | 0.63 | GAA (0.46) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL8035937 | 0.62 | GAA (0.54) | ALDH1A1HSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043339-A2 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |