Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 5/20 | 0.33 |
| ▸ | CHUK | O15111 | 5/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31265094 | 0.75 | REN (0.38) | RENIKBKBCHUKBRD4TAF1 | |
| SCHEMBL8346879 | 0.73 | REN (0.40) | RENBRD4TAF1BRPF1CREBBP | |
| SCHEMBL15629849 | 0.71 | P2RX7 (0.37) | RENPOLBHTTKDM4EALDH1A1 | |
| SCHEMBL16783918 | 0.71 | POLB (0.35) | RENPOLBHTTKDM4EALDH1A1 | |
| SCHEMBL117142 | 0.70 | HTT (0.46) | POLBHTTKDM4EALDH1A1MAPT | |
| SCHEMBL11101358 | 0.69 | KMT2A (0.41) | RENIKBKBCHUKBRD4TAF1 | |
| SCHEMBL12818798 | 0.69 | CYP2D6 (0.37) | RENBRD4TAF1BRPF1CREBBP | |
| SCHEMBL10746849 | 0.69 | REN (0.47) | RENDAOPDPK1NR3C1BCHE | |
| SCHEMBL15629848 | 0.69 | REN (0.36) | RENPOLBHTTKDM4EALDH1A1 | |
| SCHEMBL15629885 | 0.69 | CFB (0.40) | RENPOLBHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5938792-A | APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT | L'OREAL (FR) | 1999-08-17 | — | — | US | claimed |
| US-5752982-A | DYEING HAIR IN LIGHTFAST, WASHFAST COLORS | L'OREAL (FR) | 1998-05-19 | — | — | US | claimed |
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | claimed |
| EP-0580713-B1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| EP-0580713-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. | OREAL (FR) | 1994-02-02 | — | — | EP | claimed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| WO-1992018093-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1992-10-29 | — | — | WO | claimed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | claimed |
| US-5938792-A | APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT | L'OREAL (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5752982-A | DYEING HAIR IN LIGHTFAST, WASHFAST COLORS | L'OREAL (FR) | 1998-05-19 | — | — | US | disclosed |
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | disclosed |
| EP-0580713-B1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | OREAL (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0580713-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. | OREAL (FR) | 1994-02-02 | — | — | EP | disclosed |
| EP-0578735-A1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS. | OREAL (FR) | 1994-01-19 | — | — | EP | disclosed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |
| WO-1992018093-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992017157-A1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | L'OREAL (FR) | 1992-10-15 | — | — | WO | disclosed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | disclosed |