SCHEMBL8355220

SCHEMBL8355220

C=CC(=O)Oc1ccc(O)c(O)c1O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.40
THRB P10828 4/20 0.39
THRA P10827 1/20 0.39
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
PIM1 P11309 1/20 0.32
HDAC1 Q13547 1/20 0.32
HIF1A Q16665 1/20 0.32
EPAS1 Q99814 1/20 0.32
ALDH5A1 P51649 1/20 0.31
ABAT P80404 1/20 0.31
APP P05067 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31295365 0.85 HSD17B10 (0.45) TYMSTHRBTHRA
SCHEMBL8070515 0.85 HSD17B10 (0.45) TYMSTHRBTHRA
SCHEMBL28623003 0.84 THRB (0.39) TYMSTHRBTHRAMAOAMAOB
SCHEMBL2317025 0.79 THRB (0.45) TYMSTHRBTHRA
SCHEMBL824860 0.77 ESR1 (0.54) TYMSTHRBTHRA
SCHEMBL10766945 0.76 MAOB (0.47) TYMSTHRBTHRAMAOBALDH5A1
SCHEMBL4751279 0.76 THRB (0.44) TYMSTHRBTHRAALDH5A1ABAT
SCHEMBL27624619 0.76 SERPINE1 (0.41) TYMSTHRBTHRAALDH5A1ABAT
SCHEMBL218920 0.74 THRB (0.50) TYMSTHRBTHRA
SCHEMBL29497650 0.74 THRB (0.50) TYMSTHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5900352-A CARBOXYMETHYLATED B-AMINOPROPIONIC ACIDS AND SALTS AGFA-GEVAERT AG (DE) 1999-05-04 US disclosed
US-5695903-A USING AN AQUEOUS ALKALINE DEVELOPER AGFA-GEVAERT AG (DE) 1997-12-09 US disclosed