Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22782667 | 1.00 | TSHR (0.59) | TSHRALDH1A1LMNATDP1LTB4R | |
| SCHEMBL3043854 | 0.98 | TSHR (0.61) | TSHRALDH1A1LMNATDP1LTB4R | |
| SCHEMBL8752667 | 0.93 | TSHR (0.68) | TSHRLMNATDP1MEN1KMT2A | |
| SCHEMBL3046950 | 0.88 | LMNA (0.69) | TSHRALDH1A1LMNATDP1MEN1 | |
| SCHEMBL8151680 | 0.88 | LMNA (0.62) | ALDH1A1LMNALTB4RLTB4R2MEN1 | |
| SCHEMBL8158709 | 0.88 | LMNA (0.62) | ALDH1A1LMNALTB4RLTB4R2MEN1 | |
| SCHEMBL8148742 | 0.88 | LMNA (0.62) | ALDH1A1LMNALTB4RLTB4R2MEN1 | |
| SCHEMBL8163174 | 0.88 | LMNA (0.62) | ALDH1A1LMNALTB4RLTB4R2MEN1 | |
| SCHEMBL8161670 | 0.88 | LMNA (0.62) | ALDH1A1LMNALTB4RLTB4R2MEN1 | |
| SCHEMBL8162525 | 0.88 | LMNA (0.62) | ALDH1A1LMNALTB4RLTB4R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |