Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341224 | 0.92 | PREP (0.42) | PREPTPSAB1TPSD1TPSG1DPP8 | |
| SCHEMBL7294189 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7334231 | 0.83 | MAPT (0.46) | PREPITGB3KEAP1NFE2L2HTT | |
| SCHEMBL8214593 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL21171925 | 0.72 | HTT (0.67) | DPP8DPP7DPP4DPP9KEAP1 | |
| SCHEMBL8553717 | 0.72 | ITGB3 (0.51) | PREPITGB3HTTITGA2B | |
| SCHEMBL7295048 | 0.71 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL7334492 | 0.71 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL24486949 | 0.70 | HTT (0.67) | DPP8DPP7KEAP1NFE2L2HTT | |
| SCHEMBL29388202 | 0.68 | PREP (0.51) | PREPDPP8DPP7DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935963-A | (4-GUANIDINOBENZOYLAMINO)ACETYL-3-(3-(4-GUANIDINOBENZOYLAMINO) PROPYL)-2-OXOPIPERAZINE-1-ACETIC ACID OR A SALT; CONTROLLING OR INHIBITING CELL-ADHESION; PLATELET ANTIAGGREGATION WITHOUT LONG HEMORRHAGING; ANTIICHEMIC AGENTS; ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5876756-A | SUSTAINED RELEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-02 | — | — | US | disclosed |