Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295402 | 0.83 | MAPT (0.42) | MAPTKEAP1NFE2L2PREPSIGMAR1 | |
| SCHEMBL8355283 | 0.83 | PREP (0.43) | KEAP1NFE2L2PREPITGB3ITGA2B | |
| SCHEMBL7311516 | 0.81 | ITGB3 (0.46) | MAPTKEAP1NFE2L2PREPSIGMAR1 | |
| SCHEMBL7335218 | 0.81 | MAPT (0.45) | MAPTITGB3ITGA2BKLK7KLK5 | |
| SCHEMBL7286805 | 0.80 | PREP (0.43) | MAPTKEAP1NFE2L2PREPSIGMAR1 | |
| SCHEMBL7296887 | 0.80 | PREP (0.43) | MAPTKEAP1NFE2L2PREPSIGMAR1 | |
| SCHEMBL7341224 | 0.80 | PREP (0.42) | PREPITGB3HTT | |
| SCHEMBL7286648 | 0.78 | ITGB3 (0.43) | MAPTKEAP1NFE2L2PREPSIGMAR1 | |
| SCHEMBL7284719 | 0.78 | ITGB3 (0.43) | MAPTKEAP1NFE2L2PREPSIGMAR1 | |
| SCHEMBL7285021 | 0.77 | SIGMAR1 (0.44) | PREPSIGMAR1ITGB3ITGA2BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888531-A | ACTIVE MATERIAL STABILIZED WITH DISACCHARIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |