⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16086988 | 0.96 | — | — | |
| SCHEMBL27735 | 0.96 | — | — | |
| Bicarbonate SCHEMBL9660887 | 0.79 | APLNR (0.38) | — | |
| SCHEMBL26237514 | 0.77 | — | — | |
| Formic Acid SCHEMBL28084719 | 0.77 | — | — | |
| SCHEMBL10250626 | 0.75 | — | — | |
| SCHEMBL10118996 | 0.75 | — | — | |
| SCHEMBL10311268 | 0.75 | — | — | |
| SCHEMBL18526483 | 0.73 | — | — | |
| SCHEMBL24066368 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003076-A | Sulfamoyl pyrrole amides derivative and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-105452220-B | Sulfamoyl pyrrole amide derivative and application thereof as medicine for treating hepatitis B | 爱尔兰詹森科学公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-108047115-A | Pyrrole amides derivative through acetaldehyde amide substitution and its as drug for treating the purposes of hepatitis B | 爱尔兰詹森科学公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-105431413-B | Glyoxylamide-substituted pyrrole amide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-1999033790-A1 | INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS | NIHON BAYER AGROCHEM K.K. (DE) | 1999-07-08 | — | — | WO | disclosed |
| CN-1012732-B | GEN-DIHALO-1, 8-DIAMINO-4-AZA-OCTANES | MERRELL DOW PHARMA (US) | 1991-06-05 | — | — | CN | disclosed |
| CN-86105154-A | Together with-dihalo-1, the preparation method of 8-diamino-4-azepine-octane | — | 1987-04-22 | — | — | CN | disclosed |