Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150864 | 0.87 | MAPT (0.50) | MAPTALDH1A1KAT2BLMNAKMT2A | |
| SCHEMBL8350044 | 0.83 | MAPT (0.46) | MAPTALDH1A1KAT2BLMNASMN1; SMN2 | |
| SCHEMBL30808005 | 0.82 | MAPT (0.54) | MAPTALDH1A1CYP2D6KAT2BHTR6 | |
| SCHEMBL112790 | 0.82 | MAPT (0.54) | MAPTALDH1A1CYP2D6KAT2BHTR6 | |
| Bromide SCHEMBL10714879 | 0.80 | MAPT (0.51) | MAPTALDH1A1CYP2D6KAT2BHTR6 | |
| SCHEMBL2471755 | 0.79 | MAPT (0.50) | MAPTALDH1A1KAT2BHTR6LMNA | |
| Hydrochloric Acid SCHEMBL10713406 | 0.78 | MAPT (0.49) | MAPTALDH1A1KAT2BHTR6GLA | |
| SCHEMBL8349564 | 0.78 | MAPT (0.55) | MAPTALDH1A1LMNAKMT2ABCHE | |
| SCHEMBL6151746 | 0.76 | MAPT (0.40) | MAPTALDH1A1KAT2BLMNAKMT2A | |
| SCHEMBL6151858 | 0.76 | MAPT (0.40) | MAPTALDH1A1KAT2BLMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874618-A | REACTING 2-NITRO-PARAPHENYLENEDIAMINES SUBSTITUTED AT 5-POSITION BY HALOGEN ATOM WITH MERCAPTAN DERIVATIVE OR SALT IN A SOLVENT, FURTHER OXIDIZING FOR SULFUR; USEFUL AS HAIR DYE; REDUCED ALLERGIES; WASHING STABILITY | L'OREAL (FR) | 1999-02-23 | — | — | US | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5874618-A | REACTING 2-NITRO-PARAPHENYLENEDIAMINES SUBSTITUTED AT 5-POSITION BY HALOGEN ATOM WITH MERCAPTAN DERIVATIVE OR SALT IN A SOLVENT, FURTHER OXIDIZING FOR SULFUR; USEFUL AS HAIR DYE; REDUCED ALLERGIES; WASHING STABILITY | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| US-5735910-A | DIRECT HAIR DYES; WASHFASTNESS, COLORFASTNESS | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |