Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 1/20 | 0.91 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356049 | 0.97 | LMNA (0.85) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL8359273 | 0.95 | LMNA (1.00) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL8357788 | 0.92 | LMNA (0.88) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL8357750 | 0.92 | L3MBTL1 (0.90) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL7440269 | 0.92 | LMNA (0.82) | LMNATSHRL3MBTL1GAAHDAC3 | |
| SCHEMBL7201053 | 0.91 | L3MBTL1 (0.89) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL23230151 | 0.90 | LMNA (0.91) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL14302230 | 0.90 | LMNA (0.85) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL14952381 | 0.90 | LMNA (0.85) | LMNATSHRL3MBTL1HPGDGAA | |
| SCHEMBL9644621 | 0.90 | LMNA (0.91) | LMNATSHRL3MBTL1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |