Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665159 | 0.81 | CES2 (0.56) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL27514420 | 0.80 | ALOX5 (0.53) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL3407961 | 0.79 | ALOX5 (0.45) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL3559567 | 0.79 | CYP2C9 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL6197782 | 0.79 | ALOX5 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL15695572 | 0.79 | ALOX5 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL15674870 | 0.79 | CYP2C9 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL8505076 | 0.79 | ALOX5 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL11922846 | 0.79 | CYP2C9 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL14408514 | 0.79 | ALOX5 (0.51) | ALOX5ALDH1A1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874618-A | REACTING 2-NITRO-PARAPHENYLENEDIAMINES SUBSTITUTED AT 5-POSITION BY HALOGEN ATOM WITH MERCAPTAN DERIVATIVE OR SALT IN A SOLVENT, FURTHER OXIDIZING FOR SULFUR; USEFUL AS HAIR DYE; REDUCED ALLERGIES; WASHING STABILITY | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| US-5735910-A | DIRECT HAIR DYES; WASHFASTNESS, COLORFASTNESS | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |