SCHEMBL8355499

SCHEMBL8355499

Cc1cc(C)n2nc(NS(=O)(=O)c3ccccc3[N+](=O)[O-])nc2n1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.52
ALDH1A1 P00352 4/20 0.51
KDM4E B2RXH2 2/20 0.51
HPGD P15428 2/20 0.51
TSHR P16473 2/20 0.51
HSD17B10 Q99714 2/20 0.51
NFKBIA P25963 1/20 0.49
RELA Q04206 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 1/20 0.49
USP2 O75604 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PKM P14618 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 1/20 0.43
NPY5R Q15761 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355135 0.78 TSHR (0.54) POLBALDH1A1KDM4EHPGDTSHR
SCHEMBL8824776 0.75 TSHR (0.56) POLBALDH1A1TSHRSMN1; SMN2USP2
SCHEMBL8356883 0.74 SMN1; SMN2 (0.50) POLBALDH1A1KDM4EHPGDTSHR
SCHEMBL8376128 0.74 ALDH1A1 (0.53) POLBALDH1A1KDM4EHPGDTSHR
SCHEMBL6629690 0.73 KDM4E (0.54) POLBALDH1A1KDM4EHPGDTSHR
SCHEMBL9832764 0.71 TSHR (0.51) POLBALDH1A1TSHRUSP2L3MBTL1
SCHEMBL8358748 0.70 GAA (0.53) POLBALDH1A1KDM4EHPGDTSHR
SCHEMBL3546081 0.69 POLB (0.57) POLBALDH1A1NFKBIARELASMN1; SMN2
SCHEMBL11112387 0.68 POLB (0.54) POLBALDH1A1NFKBIARELASMN1; SMN2
SCHEMBL9510544 0.68 GAA (0.48) POLBALDH1A1KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP claimed
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP claimed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO claimed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO claimed
US-5880066-A COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE MONSANTO COMPANY (US) 1999-03-09 US disclosed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP disclosed
EP-0603240-B1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLUREAS MONSANTO CO (US) 1998-12-02 EP disclosed
US-5502025-A ANTIDOTES FOR HERBICIDES AND PLANT SAFTENING AGENTS MONSANTO COMPANY (US) 1996-03-26 US disclosed
US-5484760-A AMIDES MONSANTO COMPANY (US) 1996-01-16 US disclosed
EP-0603240-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1994-06-29 EP disclosed
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP disclosed
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP disclosed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO disclosed
US-4822404-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-04-18 US disclosed
US-4772720-A Process for the preparation of intermediates useful for making herbicidal sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-A)pyrimidines THE DOW CHEMICAL COMPANY (US) 1988-09-20 US disclosed
EP-0188225-B1 PROCESS FOR THE PREPARATION OF HERBICIDAL SULFONAMIDES DERIVED FROM SUBSTITUTED 2-AMINO-1,2,4 TRIAZOLO (1,5-A) PYRIMIDINES AND NOVEL INTERMEDIATES PROVIDED THEREIN THE DOW CHEMICAL COMPANY (US) 1988-01-07 EP disclosed
US-4650892-A ARYLSULFONAMIDE AND DIMETHYL N-CYANODTHIOIMINO CARBONATE THE DOW CHEMICAL COMPANY (US) 1987-03-17 US disclosed
US-4638075-A CHEMICAL INTERMEDIATES FOR TRIAZOLO (1,5A) PYRIMIDINES THE DOW CHEMICAL COMPANY (US) 1987-01-20 US disclosed
EP-0188225-A1 Process for the preparation of herbicidal sulfonamides derived from substituted 2-amino-1,2,4 triazolo (1,5-a) pyrimidines and novel intermediates provided therein THE DOW CHEMICAL COMPANY (US) 1986-07-23 EP disclosed
EP-0150974-A2 Novel sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-a)pyrimidines and compositions and methods of controlling undesired vegetation THE DOW CHEMICAL COMPANY (US) 1985-08-07 EP disclosed