Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163110 | 0.82 | ITGA4 (0.43) | SLC7A5MMEACEOPRD1OPRM1 | |
| SCHEMBL7227998 | 0.81 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine Methyl Ester SCHEMBL28118728 | 0.80 | SLC7A5 (0.50) | SLC7A5MMEOPRD1OPRM1OPRK1 | |
| SCHEMBL1422055 | 0.80 | SLC7A5 (0.64) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanyltyrosine SCHEMBL3037096 | 0.80 | MME (0.67) | SLC7A5MMEACEOPRD1OPRM1 | |
| Phenylalanyltyrosine SCHEMBL31255162 | 0.80 | MME (0.67) | SLC7A5MMEACEOPRD1OPRM1 | |
| Phenylalanyltyrosine SCHEMBL29803603 | 0.80 | MME (0.67) | SLC7A5MMEACEOPRD1OPRM1 | |
| Phenylalanyltyrosine SCHEMBL4282059 | 0.80 | MME (0.67) | SLC7A5MMEACEOPRD1OPRM1 | |
| SCHEMBL8695556 | 0.80 | MME (0.67) | SLC7A5MMEACEOPRD1OPRM1 | |
| SCHEMBL29531478 | 0.80 | MME (0.67) | SLC7A5MMEACEOPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323062-B2 | Pharmaceutical composition for the prevention and treatment of cardiovascular disease comprising the peptide having the ability to inhibit angiotensin-1 converting enzyme as an active ingredient | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2019-06-18 | — | — | US | disclosed |
| US-10308681-B2 | Pharmaceutical composition for the prevention and treatment of cardiovascular disease comprising the peptide having the ability to inhibit angiotensin-1 converting enzyme as an active ingredient | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2019-06-04 | — | — | US | disclosed |
| US-20180170961-A1 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE COMPRISING THE PEPTIDE HAVING THE ABILITY TO INHIBIT ANGIOTENSIN-1 CONVERTING ENZYME AS AN ACTIVE INGREDIENT | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2018-06-21 | — | — | US | disclosed |
| US-20150175654-A1 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE COMPRISING THE PEPTIDE HAVING THE ABILITY TO INHIBIT ANGIOTENSIN-1 CONVERTING ENZYME AS AN ACTIVE INGREDIENT | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-06-25 | — | — | US | disclosed |
| US-5922839-A | SUPPRESSING FORMATION OF ANGIOTENSIN II IN MAMMALS BY ADMINISTERING MIXTURE OF DRIED STOMACH MUCOSA AND ACIDIFYING AGENT TO PRODUCE IN SITU PEPSIN-INHIBITOR PEPTIDE OF 29 AMINO ACIDS AND MOLECULAR WEIGHT OF 3242 DALTONS | STEINER ZOLTAN W (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5688762-A | Method of treating hypertension using animal stomach mucosa extract and endogenous protease-inhibitor peptides | STEINER ZOLTAN W (DE) | 1997-11-18 | — | — | US | disclosed |