Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853134 | 0.83 | ITGA4 (0.53) | ITGA4ITGB7CTSSCTSKACE | |
| SCHEMBL2853138 | 0.83 | ITGA4 (0.53) | ITGA4ITGB7CTSSCTSKACE | |
| SCHEMBL8355604 | 0.82 | SLC7A5 (0.55) | SLC7A5ACEOPRD1OPRM1OPRK1 | |
| SCHEMBL4443858 | 0.80 | MMP9 (0.49) | ITGA4ACEMME | |
| SCHEMBL4443855 | 0.80 | MMP9 (0.49) | ITGA4ACEMME | |
| SCHEMBL630703 | 0.78 | SLC7A5 (0.57) | SLC7A5CTSSCTSK | |
| SCHEMBL594571 | 0.78 | SLC7A5 (0.57) | SLC7A5CTSSCTSK | |
| SCHEMBL7464405 | 0.78 | SLC7A5 (0.57) | SLC7A5CTSSCTSK | |
| SCHEMBL31293776 | 0.77 | OPRD1 (0.55) | ITGA4ITGB7CTSSCTSKOPRD1 | |
| Hydrochloric Acid SCHEMBL4422991 | 0.77 | SLC7A5 (0.56) | SLC7A5CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763361-A2 | STEROID SPARING AGENTS AND THEIR USE | Elan Pharmaceuticals, Inc. (US) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005097162-A2 | STEROID SPARING AGENTS AND THEIR USE | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |