Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381582 | 0.98 | SPHK1 (0.52) | SPHK1CA1CYP2D6TP53GMNN | |
| SCHEMBL6380473 | 0.98 | SPHK1 (0.52) | SPHK1CA1CYP2D6TP53GMNN | |
| SCHEMBL15718783 | 0.98 | SPHK1 (0.52) | SPHK1CA1CYP2D6TP53GMNN | |
| SCHEMBL2833774 | 0.94 | SPHK1 (0.41) | SPHK1CA1CYP2D6TP53GMNN | |
| SCHEMBL11876607 | 0.86 | SPHK1 (0.41) | SPHK1CA1CYP2D6TP53GMNN | |
| SCHEMBL17366581 | 0.85 | LMNA (0.37) | SPHK1CA1LMNACYP3A4NFKB1 | |
| SCHEMBL6381596 | 0.85 | LMNA (0.37) | SPHK1CA1LMNACYP3A4NFKB1 | |
| SCHEMBL11874858 | 0.80 | ALDH1A1 (0.41) | LMNABLMALDH1A1 | |
| SCHEMBL1703599 | 0.78 | LCK (0.46) | SPHK1CA1CYP2D6TP53GMNN | |
| SCHEMBL1703313 | 0.77 | LCK (0.48) | SPHK1CYP2D6TP53GMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001140-A | DEFOAMING AGENTS FOR PETROLEUM PRODUCTS SUCH AS DIESEL FUEL AND LUBRICATING OILS AND CRUDE OIL DEMULSIFYING AGENTS | WITCO CORPORATION (US) | 1999-12-14 | — | — | US | disclosed |
| US-4102753-A | LOWER ALKYLENE GLYCOL, LOWER OXYALKYLENE GLYCOL, OR GLYCEROL | PPG INDUSTRIES, INC. (US) | 1978-07-25 | — | — | US | disclosed |