Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 9/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354913 | 1.00 | ADAM17 (0.61) | ADAM17 | |
| SCHEMBL8354899 | 0.88 | ADAM17 (0.72) | ADAM17 | |
| SCHEMBL8353777 | 0.88 | ADAM17 (0.72) | ADAM17 | |
| SCHEMBL6741074 | 0.83 | ADAM17 (0.68) | ADAM17 | |
| SCHEMBL13648183 | 0.82 | ADAM17 (0.77) | ADAM17 | |
| SCHEMBL13648189 | 0.82 | ADAM17 (0.77) | ADAM17 | |
| SCHEMBL7650602 | 0.80 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL8353591 | 0.79 | ADAM17 (0.59) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6736529 | 0.79 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL7656290 | 0.79 | ADAM17 (0.58) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053915-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |