Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 13/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7656192 | 0.95 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL7656200 | 0.88 | ADAM17 (0.51) | ADAM17 | |
| SCHEMBL6741074 | 0.84 | ADAM17 (0.68) | ADAM17 | |
| SCHEMBL6595238 | 0.82 | ADAM17 (0.56) | ADAM17 | |
| SCHEMBL7650602 | 0.81 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL6741443 | 0.81 | ADAM17 (0.68) | ADAM17 | |
| SCHEMBL6742035 | 0.81 | ADAM17 (0.68) | ADAM17 | |
| Trifluoroacetic Acid SCHEMBL6736529 | 0.80 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL8355674 | 0.79 | ADAM17 (0.61) | ADAM17 | |
| SCHEMBL8354913 | 0.79 | ADAM17 (0.61) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376665-B1 | ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-04-23 | — | — | US | claimed |
| US-6376665-B1 | ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-04-23 | — | — | US | disclosed |