Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 8/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290311 | 0.88 | KMT2A (0.48) | KMT2AABL1RIN1PDE4DPDE4A | |
| SCHEMBL8357832 | 0.88 | KMT2A (0.48) | KMT2AABL1RIN1PDE4DPDE4A | |
| SCHEMBL7283847 | 0.87 | KMT2A (0.46) | KMT2ASTSPDE4DPDE4APDE4B | |
| SCHEMBL7280685 | 0.87 | KMT2A (0.48) | KMT2APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23411336 | 0.79 | KMT2A (1.00) | KMT2AABL1RIN1PTPN2PTPN1 | |
| SCHEMBL29157427 | 0.78 | KMT2A (0.80) | KMT2AABL1RIN1PTPN2PTPN1 | |
| SCHEMBL28434233 | 0.78 | KMT2A (0.80) | KMT2AABL1RIN1PTPN2PTPN1 | |
| SCHEMBL1651945 | 0.78 | KMT2A (0.80) | KMT2AABL1RIN1PTPN2PTPN1 | |
| SCHEMBL29967193 | 0.77 | KMT2A (0.76) | KMT2AABL1RIN1PTPN2PTPN1 | |
| SCHEMBL23411161 | 0.77 | KMT2A (0.76) | KMT2AABL1RIN1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981531-A | FOR INHIBITING PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |
| EP-0862557-A1 | SYMMETRICAL bis-HETEROARYLMETHOXYPHENYLALKYL CARBOXYLATES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997012867-A1 | SYMMETRICAL bis-HETEROARYLMETHOXYPHENYLALKYL CARBOXYLATES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-04-10 | — | — | WO | disclosed |
| US-5612373-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1997-03-18 | — | — | US | disclosed |