Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357832 | 0.92 | KMT2A (0.48) | KMT2AKDM4EPKMPDE4DPDE4A | |
| SCHEMBL7290311 | 0.88 | KMT2A (0.48) | KMT2AKDM4EPKMPDE4DPDE4A | |
| SCHEMBL8355692 | 0.87 | KMT2A (0.64) | KMT2AKDM4EPKMPDE4DPDE4A | |
| SCHEMBL7283847 | 0.84 | KMT2A (0.46) | KMT2AKDM4EPKMPDE4DPDE4A | |
| SCHEMBL8834001 | 0.80 | ITGB3 (0.67) | KDM4EPKMPDE4DPDE4APDE4B | |
| SCHEMBL8357838 | 0.76 | KMT2A (0.33) | KMT2AKDM4EPKMPDE4DPDE4A | |
| SCHEMBL8832736 | 0.75 | ITGB3 (0.60) | KDM4EPKMPDE4DPDE4APDE4B | |
| SCHEMBL8832973 | 0.74 | ITGB3 (0.47) | KDM4EPKMGPR119ITGB3ITGA2B | |
| SCHEMBL8833238 | 0.74 | ITGB3 (0.58) | KDM4EPKMPDE4DPDE4APDE4B | |
| SCHEMBL1725187 | 0.73 | PDE4D (0.45) | KMT2AKDM4EPKMPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981531-A | FOR INHIBITING PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |
| EP-0632016-B1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LTD (GB) | 1997-04-09 | — | — | EP | disclosed |
| US-5612373-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1997-03-18 | — | — | US | disclosed |
| WO-1995000472-A1 | 1,2 DIACYLATED HYDRAZINE DERIVATIVES AND THEIR USE AS ALL ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1995-01-05 | — | — | WO | disclosed |
| EP-0632016-A1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |