Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.49 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926027 | 0.94 | TSHR (0.71) | TSHRMAOBMAOALTB4RMAPT | |
| SCHEMBL11802724 | 0.86 | MAOB (0.72) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL28557828 | 0.86 | MAPT (0.54) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL28564924 | 0.84 | MAPT (0.55) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL108114 | 0.81 | MAOB (0.74) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL1520283 | 0.81 | TSHR (1.00) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL2729496 | 0.80 | FKBP1A (0.63) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL18686184 | 0.80 | TSHR (0.52) | TSHRMAOBMAOALTB4RMAPT | |
| SCHEMBL107322 | 0.79 | MAOB (0.83) | TSHRMAOBMAOAMAPTALDH1A1 | |
| SCHEMBL11039281 | 0.79 | MAOB (0.62) | TSHRMAOBMAOAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |