Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557828 | 0.99 | MAPT (0.54) | MAPTTSHRNPSR1MAOBMAOA | |
| SCHEMBL28564398 | 0.92 | TSHR (0.61) | MAPTTSHRNPSR1MAOBMAOA | |
| SCHEMBL15487116 | 0.85 | MAPT (0.54) | MAPTTSHRNPSR1ALDH1A1LMNA | |
| SCHEMBL8355712 | 0.84 | TSHR (0.68) | MAPTTSHRMAOBMAOAALDH1A1 | |
| SCHEMBL28566805 | 0.82 | FKBP1A (0.60) | MAPTTSHRNPSR1MAOBALDH1A1 | |
| SCHEMBL11802724 | 0.82 | MAOB (0.72) | MAPTTSHRMAOBMAOAALDH1A1 | |
| SCHEMBL8282265 | 0.81 | MAPT (0.58) | MAPTTSHRNPSR1ALDH1A1LMNA | |
| SCHEMBL2926027 | 0.81 | TSHR (0.71) | MAPTTSHRMAOBMAOAALDH1A1 | |
| SCHEMBL28490944 | 0.80 | MAOB (0.64) | MAPTTSHRNPSR1MAOBMAOA | |
| SCHEMBL108114 | 0.80 | MAOB (0.74) | MAPTTSHRMAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407801-B | 3, 4-methylenedioxy phenoxy fibrate- (3, 4-methylenedioxy) phenyl ester compound and application thereof in reducing blood fat | 陕西中医药大学 | 2020-12-22 | — | — | CN | disclosed |