SCHEMBL835587

SCHEMBL835587

COc1cccc2c(C(C)=O)cccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
GAA P10253 1/20 0.58
CDC25B P30305 2/20 0.54
PLK1 P53350 1/20 0.53
LMNA P02545 2/20 0.51
HPGDS O60760 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
HPGD P15428 2/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KCNK3 O14649 1/20 0.47
KCNK9 Q9NPC2 1/20 0.47
KDM4E B2RXH2 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4518755 0.89 PLK1 (0.67) MAPTGAACDC25BPLK1LMNA
SCHEMBL4103770 0.85 CDC25B (0.68) MAPTGAACDC25BPLK1HPGDS
SCHEMBL38573232 0.83 KDM4E (0.55) MAPTGAAPLK1LMNASMN1; SMN2
SCHEMBL7119411 0.83 KDM4E (0.55) MAPTGAAPLK1LMNASMN1; SMN2
SCHEMBL14999028 0.83 ESR1 (0.54) MAPTGAACDC25BPLK1LMNA
SCHEMBL30742625 0.83 CDC25B (0.53) MAPTGAACDC25BPLK1LMNA
SCHEMBL4099121 0.83 PLK1 (0.56) MAPTGAACDC25BPLK1LMNA
SCHEMBL10964177 0.83 CDC25B (0.53) MAPTCDC25BPLK1HPGDSESR1
SCHEMBL30742694 0.83 PLK1 (0.56) MAPTGAACDC25BPLK1LMNA
SCHEMBL30742731 0.83 CDC25B (0.53) MAPTCDC25BPLK1HPGDSESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249203-A1 RESIN-MADE PIPE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-27 EP disclosed
US-20170141372-A1 POROUS LAYER FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SEPARATOR, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY LAMINATED SEPARATOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 US disclosed
US-9283707-B2 Method for producing liquid-crystalline polyester resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-15 US disclosed
US-9040706-B2 Pyrrolidine inhibitors of IAP GENENTECH, INC. (US) 2015-05-26 US disclosed
US-9040706-B2 Pyrrolidine inhibitors of IAP GENENTECH, INC. (US) 2015-05-26 US disclosed
US-8946557-B2 Multilayer insulated electric wire and transformer using the same FURUKAWA ELECTRIC CO., LTD. (JP) 2015-02-03 US disclosed
US-20140080805-A1 PYRROLIDINE INHIBITORS OF IAP GENENTECH, INC. (US) 2014-03-20 US disclosed
US-20140080805-A1 PYRROLIDINE INHIBITORS OF IAP GENENTECH, INC. (US) 2014-03-20 US disclosed
US-8658057-B2 Liquid crystal polyester resin composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-02-25 US disclosed
EP-1836201-B2 PYRROLIDINE INHIBITORS OF IAP GENENTECH INC (US) 2013-09-04 EP disclosed
US-7344657-B2 comprises at least one compound selected from an aliphatic carboxylate aryl ester and an aromatic carboxylic anhydride; and a solvent containing at least 30% by weight of a halogen-substituted phenol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20080021146-A1 Thermal conductive resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-24 US disclosed
US-20070225420-A1 Granule useful for highly thermal-conductive resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-09-27 US disclosed
US-20070219301-A1 Liquid-Crystal Polyester Resin Composition SUMITOMO CHEMICAL CO., LTD. (JP) 2007-09-20 US disclosed
US-20070173565-A1 Wholly aromatic liquid crystal polyester resin composition and optical pickup lens holder ENEOS MATERIALS CORPORATION (JP) 2007-07-26 US disclosed
US-7247590-B2 Composite dielectric, composite dielectric sheet, composite dielectric paste, metal-layered composite dielectric, wiring board and multilayer wiring board TDK CORPORATION (JP) 2007-07-24 US disclosed
US-7223807-B2 High dielectric resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-29 US disclosed
US-7211527-B2 Resin-impregnated substrate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-01 US disclosed
US-20070077416-A1 Substrate for flexible wiring and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-05 US disclosed
US-7193020-B2 Film and laminate of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140080805-A1 PYRROLIDINE INHIBITORS OF IAP BIRC5, XIAP, BIRC2 MAPT 2677/4885GAA 1437/4885CDC25B 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.