Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553810 | 0.93 | MAPT (0.57) | MAPTLMNAALDH1A1TSHRMEN1 | |
| SCHEMBL11484097 | 0.93 | MAPT (0.61) | MAPTLMNAALDH1A1TSHRMEN1 | |
| SCHEMBL6673597 | 0.91 | MAPT (0.55) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9651161 | 0.91 | MAPT (0.59) | MAPTLMNAALDH1A1TSHRMEN1 | |
| SCHEMBL8438191 | 0.87 | ALDH1A1 (0.51) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5562501 | 0.87 | MAPT (0.59) | MAPTLMNAALDH1A1TSHRMEN1 | |
| SCHEMBL11013467 | 0.87 | MAPT (0.55) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16543579 | 0.87 | MAPT (0.55) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16431683 | 0.87 | MAPT (0.55) | MAPTLMNAALDH1A1TSHRMEN1 | |
| SCHEMBL1538970 | 0.87 | MAPT (0.55) | MAPTLMNAALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013116823-A1 | BENZIMIDAZOLES AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-08-08 | — | — | WO | disclosed |
| WO-2013116823-A1 | BENZIMIDAZOLES AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-08-08 | — | — | WO | disclosed |
| US-5910578-A | NOVEL AZO DYES USEFUL FOR DYEING OR PRINTING SYNTHETIC MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-08 | — | — | US | disclosed |