SCHEMBL6673597

SCHEMBL6673597

CCOc1cc([N+](=O)[O-])c(OCC)cc1N

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.55
LMNA P02545 4/20 0.55
ALDH1A1 P00352 3/20 0.55
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPK1 P28482 2/20 0.44
POLB P06746 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
USP2 O75604 1/20 0.42
RAB9A P51151 1/20 0.42
GAA P10253 1/20 0.42
CREBBP Q92793 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438191 0.92 ALDH1A1 (0.51) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11553810 0.91 MAPT (0.57) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL8356136 0.91 MAPT (0.61) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL9651161 0.90 MAPT (0.59) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11484097 0.88 MAPT (0.61) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11835695 0.85 MAPT (0.53) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL23110719 0.85 ALDH1A1 (0.53) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL10940683 0.85 MAPT (0.52) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL11581876 0.83 MAPT (0.49) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL20987168 0.82 MAPT (0.51) MAPTLMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1172356-B1 Process for producing N-acylnitroaniline derivative SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6630598-B2 Reacting nitroaniline compound with acid chloride/anhydride in presence of alkali metal/earth metal compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-07 US disclosed
US-6551529-B2 Bisazo compound of a specific structure; oriented to a definite direction such that the dye can polarize a light passed therethrough FUJI PHOTO FILM CO., LTD. (JP) 2003-04-22 US disclosed
US-20020084447-A1 Dichromatic polarizing element and production method thereof FUJIFILM CORPORATION (JP) 2002-07-04 US disclosed
EP-0747449-B1 BISAZO COMPOUND MERCK PATENT GMBH (DE) 2002-06-12 EP disclosed
US-20020016506-A1 Process for producing N-acylnitroaniline derivative SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-07 US disclosed
EP-1172356-A1 Process for producing N-acylnitroaniline derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-16 EP disclosed
US-5717080-A NONTOXIC FUJI IMMUNOPHARMACEUTICALS CORP. (US) 1998-02-10 US disclosed
EP-0747449-A1 BISAZO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-12-11 EP disclosed
EP-0416118-B1 PRODUCTION OF p-PHENYLENEDIAMINES NIPPON KAYAKU KK (JP) 1993-12-29 EP disclosed
US-4156086-A INTERMEDIATES FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4079052-A Diazopigments containing pyridine derivatives CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-4038268-A DIAZOTIZATION, COUPLING BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-4006128-A CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3957749-A WATER-INSOLUBLE MONOAZO PYRIDINE DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed
US-3957860-A SULFAMIC ACID CIBA-GEIGY AG (CH) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016506-A1 Process for producing N-acylnitroaniline derivative NAAA, NAT1, ACOT7 MAPT 2912/4885LMNA 1607/4885ALDH1A1 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.