SCHEMBL8356152

SCHEMBL8356152

O=C(NCCN1CCOCC1)c1cc2ccccc2cc1O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.68
CYP2D6 P10635 1/20 0.68
CYP2C19 P33261 1/20 0.68
KMT2A Q03164 2/20 0.68
KDM4E B2RXH2 3/20 0.61
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 2/20 0.61
HPGD P15428 2/20 0.59
TSHR P16473 1/20 0.59
MAOA P21397 1/20 0.59
MAOB P27338 1/20 0.59
MAPT P10636 1/20 0.59
CASP1 P29466 1/20 0.59
CASP7 P55210 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MEN1 O00255 1/20 0.59
HPGDS O60760 1/20 0.57
CD274 Q9NZQ7 1/20 0.57
POLR1A O95602 1/20 0.57
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580300 0.93 ALDH1A1 (0.69) CYP1A2CYP2D6CYP2C19KMT2AKDM4E
Hydrochloric Acid SCHEMBL10348659 0.92 ALDH1A1 (0.68) CYP1A2CYP2D6CYP2C19KMT2AKDM4E
SCHEMBL10336968 0.89 KDM4E (0.64) CYP1A2CYP2D6CYP2C19KMT2AKDM4E
SCHEMBL11338593 0.87 TSHR (0.59) CYP1A2CYP2D6CYP2C19KMT2AHPGD
SCHEMBL11338560 0.87 CYP2C19 (0.61) CYP1A2CYP2D6CYP2C19KMT2AALDH1A1
SCHEMBL8350584 0.87 MAPT (0.62) CYP1A2CYP2D6CYP2C19KMT2AKDM4E
SCHEMBL31298077 0.84 KMT2A (0.67) CYP1A2CYP2D6CYP2C19KMT2AALDH1A1
SCHEMBL10880905 0.83 CYP2C19 (0.53) CYP1A2CYP2D6CYP2C19KMT2AKDM4E
SCHEMBL10336967 0.83 ALDH1A1 (0.60) CYP1A2CYP2D6CYP2C19KMT2AKDM4E
SCHEMBL10819820 0.82 KMT2A (0.62) CYP1A2CYP2D6CYP2C19KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4304831-A ELECTROGRAPHY; COPIES RICOH CO., LTD. (JP) 1981-12-08 US claimed
US-8969026-B2 Polymeric reverse micelles as selective extraction agents and related methods of MALDI-MS analysis UNIVERSITY OF MASSACHUSETTS (US) 2015-03-03 US disclosed
US-8969026-B2 Polymeric reverse micelles as selective extraction agents and related methods of MALDI-MS analysis UNIVERSITY OF MASSACHUSETTS (US) 2015-03-03 US disclosed
US-20120183983-A1 Polymeric Reverse Micelles as Selective Extraction Agents and Related Methods of MALDI-MS Analysis UNIVERSITY OF MASSACHUSETTS 2012-07-19 US disclosed
US-20120183983-A1 Polymeric Reverse Micelles as Selective Extraction Agents and Related Methods of MALDI-MS Analysis UNIVERSITY OF MASSACHUSETTS 2012-07-19 US disclosed
WO-2009023158-A2 POLYMERIC REVERSE MICELLES AS SELECTIVE EXTRACTION AGENTS AND RELATED METHODS OF MALDI-MS ANALYSIS UNIVERSITY OF MASSACHUSETTS (US) 2009-02-19 WO disclosed
US-5935757-A HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1999-08-10 US disclosed
US-4304831-A ELECTROGRAPHY; COPIES RICOH CO., LTD. (JP) 1981-12-08 US disclosed
US-4225662-A 5-(ACETOACETAMIDO)BENZIMIDAZOLIN-2-ONE YELLOW COUPLERS RICOH COMPANY, LTD. (JP) 1980-09-30 US disclosed
US-4155762-A ALKALI OR ALKALINE EARTH METAL SALT OF AMINO CARBOXYLIC OR SULFONIC ACID RICOH CO., LTD. (JP) 1979-05-22 US disclosed
US-3944423-A Light-sensitive diazotype material comprising a fluoroalkoxy-substituted diazonium compound KEUFFEL & ESSER COMPANY (US) 1976-03-16 US disclosed