Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238408 | 0.94 | LMNA (0.69) | TSHRLMNAKMT2AMAPK1MAOA | |
| SCHEMBL8356152 | 0.87 | CYP1A2 (0.68) | TSHRLMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11338560 | 0.87 | CYP2C19 (0.61) | LMNACYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL4580300 | 0.81 | ALDH1A1 (0.69) | TSHRLMNACYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL10348659 | 0.80 | ALDH1A1 (0.68) | TSHRLMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17678082 | 0.79 | LMNA (0.67) | TSHRLMNAKMT2AABL1RIN1 | |
| SCHEMBL21619352 | 0.79 | LMNA (0.67) | TSHRLMNACYP2C19KMT2AABL1 | |
| SCHEMBL4579225 | 0.79 | LMNA (0.61) | TSHRLMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10881735 | 0.77 | KDM4E (0.54) | LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10336968 | 0.77 | KDM4E (0.64) | TSHRLMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304831-A | ELECTROGRAPHY; COPIES | RICOH CO., LTD. (JP) | 1981-12-08 | — | — | US | claimed |
| US-4304831-A | ELECTROGRAPHY; COPIES | RICOH CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4225662-A | 5-(ACETOACETAMIDO)BENZIMIDAZOLIN-2-ONE YELLOW COUPLERS | RICOH COMPANY, LTD. (JP) | 1980-09-30 | — | — | US | disclosed |