Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56986 | 0.91 | TDP1 (0.59) | MAPK1L3MBTL1ALDH1A1IDO1OPRK1 | |
| SCHEMBL14368556 | 0.87 | TDP1 (0.61) | MAPK1L3MBTL1ALDH1A1HDAC6CASP1 | |
| SCHEMBL3906464 | 0.85 | ALOX5 (0.56) | HDAC6SMN1; SMN2ALOX5TYR | |
| SCHEMBL14793821 | 0.84 | TRPV1 (0.57) | MAPK1L3MBTL1ALDH1A1HDAC6CASP1 | |
| SCHEMBL8350924 | 0.84 | CYP4F2 (0.60) | ALDH1A1HDAC6HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL19889918 | 0.83 | ALOX5 (0.57) | MAPK1L3MBTL1ALDH1A1CASP1TDP1 | |
| SCHEMBL19007852 | 0.82 | ALDH1A1 (0.59) | MAPK1L3MBTL1ALDH1A1HDAC6CASP1 | |
| SCHEMBL18673 | 0.82 | ALDH1A1 (0.68) | MAPK1L3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL3963428 | 0.82 | ALDH1A1 (0.68) | MAPK1L3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL28151357 | 0.81 | HDAC6 (0.57) | ALDH1A1HDAC6AKR1B10AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283658-C | Proline ester and transdermal preparation containing the same | TOAEIYO LTD (JP) | 2006-11-08 | — | — | CN | disclosed |
| CN-1681839-A | Proline ester and transdermal preparation containing the same | TOAEIYO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| CN-1196731-A | Di-glycosylated 1, 2-diols as mimetics of sialyl-lewis X and sialyl-lewis A | NOVARTIS AG (CH) | 1998-10-21 | — | — | CN | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| CN-1019803-B | 1,3, the preparation method of 4-thiadiazoles derivative | FISONS PLC (GB) | 1992-12-30 | — | — | CN | disclosed |
| CN-87101916-A | The preparation method of pharmaceutically active compounds | — | 1988-08-24 | — | — | CN | disclosed |