Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30375449 | 0.90 | SMN1; SMN2 (0.62) | TDP1SMN1; SMN2S1PR2S1PR1S1PR3 | |
| SCHEMBL28553022 | 0.88 | SMN1; SMN2 (0.52) | TDP1SMN1; SMN2S1PR2S1PR1S1PR3 | |
| SCHEMBL13073866 | 0.82 | TDP1 (0.65) | TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL28983266 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL5547338 | 0.80 | TDP1 (0.62) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL29049842 | 0.80 | LMNA (0.63) | TDP1SMN1; SMN2S1PR2S1PR1S1PR3 | |
| SCHEMBL27753481 | 0.79 | TDP1 (0.66) | TDP1SMN1; SMN2KMT2ASLC6A2SLC6A3 | |
| SCHEMBL416566 | 0.79 | TDP1 (0.91) | TDP1SMN1; SMN2KMT2ASLC6A2SLC6A3 | |
| SCHEMBL223441 | 0.79 | TDP1 (1.00) | TDP1SMN1; SMN2KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9377743 | 0.79 | TDP1 (0.70) | TDP1SMN1; SMN2KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759673-B | Catalyst for olefin polymerization, catalyst component and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-112759674-B | Catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-112759673-B | Catalyst for olefin polymerization, catalyst component and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |