Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695954 | 0.89 | MEN1 (0.55) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL8444246 | 0.87 | MAPT (0.62) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL11428955 | 0.84 | MAPT (0.49) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL6825011 | 0.83 | MAPT (0.56) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL1884093 | 0.83 | MEN1 (0.56) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL10781092 | 0.81 | MAPT (0.53) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL5695946 | 0.81 | TOP2B (0.65) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL20334218 | 0.81 | TOP2B (0.50) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL8053208 | 0.80 | MAPT (0.66) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR | |
| SCHEMBL13995639 | 0.80 | MAPT (0.65) | MAPTMAPK1L3MBTL1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5961664-A | THREE 1,4-HYDROXYALKYLAMINO-ANTHRAQUINONE DERIVATIVES, WHEREIN TWO OF THE ANTHRAQUINONE COMPOUNDS IN THE MIXTURE ARE SYMMETRIC AND THE OTHER ANTHRAQUINONE COMPOUND IS ASYMMETRIC, AND WHEREIN EACH OF THE ANTHRAQUINONE COMPOUNDS HAS SIMILAR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | claimed |
| US-5961664-A | THREE 1,4-HYDROXYALKYLAMINO-ANTHRAQUINONE DERIVATIVES, WHEREIN TWO OF THE ANTHRAQUINONE COMPOUNDS IN THE MIXTURE ARE SYMMETRIC AND THE OTHER ANTHRAQUINONE COMPOUND IS ASYMMETRIC, AND WHEREIN EACH OF THE ANTHRAQUINONE COMPOUNDS HAS SIMILAR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | disclosed |