SCHEMBL835688

SCHEMBL835688

COc1ccc(OC)c(-c2ccccc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
MAPK1 P28482 1/20 0.62
RECQL P46063 1/20 0.62
HDAC4 P56524 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
CYP1A1 P04798 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2E1 P05181 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C8 P10632 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2A6 P11509 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP4B1 P13584 1/20 0.56
CYP2B6 P20813 1/20 0.56
CYP3A5 P20815 1/20 0.56
CYP2A7 P20853 1/20 0.56
CYP3A7 P24462 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572032 1.00 KDM4E (0.64) KDM4EL3MBTL1MAPK1RECQLHDAC4
Iodide SCHEMBL30084369 0.98 KDM4E (0.62) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL8501330 0.96 L3MBTL1 (0.60) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL29386715 0.91 KDM4E (0.59) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL29899709 0.90 CA12 (0.60) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL29384037 0.88 CYP1A1 (0.72) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL6163752 0.88 KDM4E (0.60) KDM4EL3MBTL1MAPK1RECQLHDAC4
Propionaldehyde SCHEMBL28150888 0.87 HDAC8 (0.52) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL5828214 0.85 L3MBTL1 (0.50) KDM4EL3MBTL1MAPK1RECQLHDAC4
SCHEMBL5632975 0.84 CYP1A1 (0.79) KDM4EL3MBTL1MAPK1RECQLCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111211327-B Compound for lithium ion battery anode material and preparation method and application thereof 天津大学 2022-10-25 CN claimed
CN-111211327-A Compound for lithium ion battery anode material and preparation method and application thereof 天津大学 2020-05-29 CN claimed
CN-106795191-A Novel precatalyst scaffolds for crosslinking reactions and methods of making and using same 耶鲁大学 2017-05-31 CN claimed
CN-105974733-A Negative-type photosensitive resin composition, pattern formed by using the same and image display device 东友精细化工有限公司 2016-09-28 CN claimed
WO-2006093467-A1 CONJUGATED ORGANIC MOLECULES FOR MOLECULAR ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-09-08 WO claimed
WO-2000071572-A1 SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 2000-11-30 WO claimed
US-11877395-B2 Thermoplastic liquid crystal polymer film and circuit board using same KURARAY CO., LTD. (JP) 2024-01-16 US disclosed
US-20230399773-A1 CORE-SHEATH COMPOSITE FIBER, PRODUCTION METHOD THEREFOR, AND FIBER STRUCTURE KURARAY CO., LTD. (JP) 2023-12-14 US disclosed
US-11825284-B2 Acoustic diaphragm, manufacturing method therefor, and acoustic device KURARAY CO., LTD. (JP) 2023-11-21 US disclosed
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 US disclosed
US-20230332350-A1 DOUBLE BRAID ROPE STRUCTURE KURARAY CO., LTD. (JP) 2023-10-19 US disclosed
US-20230332334-A1 LIQUID CRYSTAL POLYESTER FIBERS AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2023-10-19 US disclosed
US-20230323570-A1 METHOD OF PRODUCING MELT-ANISOTROPIC AROMATIC POLYESTER MULTIFILAMENT KURARAY CO., LTD. (JP) 2023-10-12 US disclosed
US-7247590-B2 Composite dielectric, composite dielectric sheet, composite dielectric paste, metal-layered composite dielectric, wiring board and multilayer wiring board TDK CORPORATION (JP) 2007-07-24 US disclosed
US-7223807-B2 High dielectric resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-29 US disclosed
US-7211527-B2 Resin-impregnated substrate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-01 US disclosed
US-20070077416-A1 Substrate for flexible wiring and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-05 US disclosed
US-7193020-B2 Film and laminate of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-20 US disclosed
US-6645939-B1 Very late antigen-4 (VLA) integrin antagonists; antiallergens, antiasthmatics, and antiinflammatory agents; multiple sclerosis, autoimmune disease treatment MERCK & CO., INC. 2003-11-11 US disclosed
WO-2000071572-A1 SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 2000-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KDM5C, DHX15, KDM5A KDM4E 135/4885L3MBTL1 4800/4885MAPK1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.