Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 11/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330443 | 0.89 | REN (0.55) | RENACEF2PRSS1CMA1 | |
| SCHEMBL14440148 | 0.85 | REN (0.52) | RENACEF2PRSS1CMA1 | |
| SCHEMBL8265650 | 0.85 | REN (0.59) | RENACEF2PRSS1CMA1 | |
| SCHEMBL8265581 | 0.85 | REN (0.59) | RENACEF2PRSS1CMA1 | |
| SCHEMBL2475863 | 0.83 | REN (0.55) | RENACEF2PRSS1CMA1 | |
| SCHEMBL8255495 | 0.83 | REN (0.55) | RENACEF2PRSS1CMA1 | |
| SCHEMBL8261170 | 0.83 | REN (0.55) | RENACEF2PRSS1CMA1 | |
| SCHEMBL22698803 | 0.83 | REN (0.55) | RENACEF2PRSS1CMA1 | |
| SCHEMBL8165627 | 0.83 | REN (0.55) | RENACEF2PRSS1CMA1 | |
| SCHEMBL971479 | 0.83 | REN (0.55) | RENACEF2PRSS1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022072-A1 | BORONIC ACID SALTS ANT THEIR USE IN THE TREATMENT OF THROMBOSIS | TRIGEN LIMITED (GB) | 2004-03-18 | — | — | WO | disclosed |