Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976312 | 0.91 | ALDH1A1 (0.42) | FFAR1AKR1B1ALDH1A1KDM4EBRS3 | |
| SCHEMBL3978309 | 0.85 | FFAR1 (0.43) | FFAR1AKR1B1ALDH1A1KDM4EAGTR2 | |
| SCHEMBL8359613 | 0.84 | FFAR1 (0.41) | FFAR1AKR1B1ALDH1A1KDM4EBRS3 | |
| SCHEMBL7376271 | 0.83 | ALDH1A1 (0.42) | FFAR1AKR1B1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8635574 | 0.79 | FFAR1 (0.40) | FFAR1AKR1B1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7260709 | 0.78 | TSHR (0.49) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL8476711 | 0.76 | KDM4E (0.39) | L3MBTL1ALDH1A1KDM4EBRS3PPARG | |
| SCHEMBL5592930 | 0.75 | BRS3 (0.39) | FFAR1AKR1B1ALDH1A1KDM4EBRS3 | |
| SCHEMBL28394764 | 0.75 | PPARG (0.38) | FFAR1AKR1B1BRS3EGLN1PPARG | |
| SCHEMBL8419218 | 0.74 | MEN1 (0.38) | L3MBTL1ALDH1A1KDM4EBRS3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |