Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592930 | 0.79 | BRS3 (0.39) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL8357464 | 0.79 | FFAR1 (0.43) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL12475515 | 0.77 | BRS3 (0.45) | FFAR1AKR1B1EGLN1BRS3AGTR1 | |
| SCHEMBL8359682 | 0.76 | FFAR1 (0.38) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL3976312 | 0.75 | ALDH1A1 (0.42) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL8476707 | 0.75 | KDM4E (0.41) | FFAR1AKR1B1ALDH1A1KDM4EBRS3 | |
| SCHEMBL8357465 | 0.74 | BRS3 (0.45) | FFAR1AKR1B1EGLN1BRS3AGTR1 | |
| SCHEMBL7376271 | 0.72 | ALDH1A1 (0.42) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL3978309 | 0.71 | FFAR1 (0.43) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL9303359 | 0.71 | HPGD (0.39) | FFAR1AKR1B1ALDH1A1KDM4EBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705517-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |