SCHEMBL8357930

SCHEMBL8357930

C[SiH](C)[Zr](Cl)(Cl)(C1(c2ccccc2)C(c2ccccc2)=Cc2ccccc21)C1(c2ccccc2)C(c2ccccc2)=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355617 0.82
SCHEMBL7946149 0.69
SCHEMBL8361880 0.69 ESR1 (0.35) ESR1ESR2
SCHEMBL232989 0.68 ESR1 (0.43) ESR1ESR2
SCHEMBL7026730 0.65 ESR1 (0.41) ESR1ESR2
Hydrochloric Acid SCHEMBL6285729 0.64 ESR1 (0.40) ESR1ESR2
SCHEMBL28814696 0.63 ESR1 (0.42) ESR1ESR2
SCHEMBL6285727 0.63 ESR1 (0.39) ESR1ESR2
SCHEMBL6289887 0.63 ESR1 (0.39) ESR1ESR2
SCHEMBL28815084 0.62 ESR1 (0.44) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912373-A Process for converting the achiral meso form of an ansa-metallocene complex into the chiral racemic form BASF AKTIENGESELLSCHAFT (DE) 1999-06-15 US disclosed
US-5892081-A REACTING TIN METALLOCENE WITH TRANSITION METAL HALIDE OR ALKOXIDE BASF AKTIENGESELLSCHAFT (DE) 1999-04-06 US disclosed
US-5840950-A Process for converting the achiral meso form or the racemate of an ansa-metallocene complex or mixtures thereof into one of its enantiomers BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed