SCHEMBL232989

SCHEMBL232989

C1=C(c2ccccc2)C(c2ccccc2)(c2ccccc2)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.31
KIF11 P52732 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24368694 0.87 ESR1 (0.36) ESR1ESR2ALDH1A1KIF11KDM4E
SCHEMBL24368497 0.87 ESR1 (0.36) ESR1ESR2ALDH1A1KIF11KDM4E
SCHEMBL24369027 0.87 ESR1 (0.36) ESR1ESR2ALDH1A1KIF11KDM4E
SCHEMBL13475650 0.86 ESR1 (0.35) ESR1ESR2LMNAALDH1A1KDM4E
SCHEMBL24368502 0.85 ALDH1A1 (0.35) ESR1ESR2LMNAALDH1A1KDM4E
SCHEMBL22214695 0.81 ESR1 (0.36) ESR1ESR2LMNAALDH1A1KDM4E
SCHEMBL24368499 0.78 ESR1 (0.35) ESR1ESR2ALDH1A1KDM4EMEN1
SCHEMBL24368695 0.78 ESR1 (0.35) ESR1ESR2ALDH1A1KDM4EMEN1
SCHEMBL13475657 0.78 ESR1 (0.34) ESR1ESR2
SCHEMBL16482577 0.78 LMNA (0.37) LMNAKDM4EMEN1MAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115776981-A Material for organic electroluminescent device 默克专利有限公司 2023-03-10 CN claimed
US-20220416164-A1 NITROGEN-CONTAINING COMPOUNDS, ELECTRONIC ELEMENTS AND ELECTRONIC DEVICES SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-12-29 US claimed
CN-115087654-A Material for organic electroluminescent device 默克专利有限公司 2022-09-20 CN claimed
CN-114787173-A Metal complexes 默克专利有限公司 2022-07-22 CN claimed
CN-114516803-A Fused ring compound and application thereof 宁波卢米蓝新材料有限公司 2022-05-20 CN claimed
CN-111902409-A Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2020-11-06 CN claimed
CN-111788177-A Spirobenzanthracene-fluorene derivatives and their use in organic electronic devices, display and lighting devices 诺瓦尔德股份有限公司 2020-10-16 CN claimed
CN-111770922-A Organic electronic device, display and lighting apparatus including the same 诺瓦尔德股份有限公司 2020-10-13 CN claimed
CN-111683948-A Phenanthroline compound and organic light emitting device including the same 株式会社进雄产业 2020-09-18 CN claimed
CN-111564567-A Organic light emitting element 三星显示有限公司 2020-08-21 CN claimed
CN-111417639-A Material for organic electroluminescent device 默克专利有限公司 2020-07-14 CN claimed
EP-1422225-B1 BENZOISOSELENAZOLE DERIVATIVES WITH ANTI-INFLAMMATION, ANTINEOPLASTIC AND ANTI-THROMBOSIS ACTIVITY AND THEIR USE UNIV BEIJING (CN) 2012-01-04 EP claimed
US-20090117204-A1 BENZOISOSELENAZOLE DERIVATIVES WITH ANTI-INFLAMMATION, ANTIVIRUS AND ANTITHROMBOSIS ACTIVITY AND THEIR USE PEKING UNIVERSITY (CN) 2009-05-07 US claimed
US-7495019-B2 Benzoisoselenazole derivatives with anti-inflammation, antivirus and antithrombosis activity and their use PEKING UNIVERSITY (CN) 2009-02-24 US claimed
US-20050014801-A1 Benzoisoselenazole derivatives with anti-inflammation, antivirus and antithrombosis activity and their use PEKING UNIVERSITY (CN) 2005-01-20 US claimed
EP-1422225-A1 BENZOISOSELENAZOLE DERIVATIVES WITH ANTI-INFLAMMATION, ANTIVIRUS AND ANTI-THROMBOSIS ACTIVITY AND THEIR USE Peking University (CN) 2004-05-26 EP claimed
CN-110036498-B Method for manufacturing electronic device 默克专利有限公司 2023-04-18 CN disclosed
CN-115956073-A Material for organic electroluminescent device 默克专利有限公司 2023-04-11 CN disclosed
US-20050014801-A1 Benzoisoselenazole derivatives with anti-inflammation, antivirus and antithrombosis activity and their use PEKING UNIVERSITY (CN) 2005-01-20 US disclosed
EP-1422225-A1 BENZOISOSELENAZOLE DERIVATIVES WITH ANTI-INFLAMMATION, ANTIVIRUS AND ANTI-THROMBOSIS ACTIVITY AND THEIR USE Peking University (CN) 2004-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090117204-A1 BENZOISOSELENAZOLE DERIVATIVES WITH ANTI-INFLAMMATION, ANTIVIRUS AND ANTITHROMBOSIS ACTIVITY AND THEIR USE SERPINC1, IL33, SERPINB1 ESR1 1935/4885ESR2 1552/4885LMNA 2721/4885
US-20050014801-A1 Benzoisoselenazole derivatives with anti-inflammation, antivirus and antithrombosis activity and their use SERPINC1, IL33, SERPINB1 ESR1 1935/4885ESR2 1552/4885LMNA 2721/4885
US-20220416164-A1 NITROGEN-CONTAINING COMPOUNDS, ELECTRONIC ELEMENTS AND ELECTRONIC DEVICES NPPA, NES, INA ESR1 32/4885ESR2 265/4885LMNA 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.