SCHEMBL8358015

SCHEMBL8358015

C=CCCC1(c2ccc(C3CCCCC3)cc2)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 10/20 0.34
SLC6A4 P31645 8/20 0.34
CYP3A4 P08684 2/20 0.34
SLC6A2 P23975 5/20 0.33
HAO1 Q9UJM8 1/20 0.33
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3480990 0.78 CNR2 (0.42) SLC6A3SLC6A4SLC6A2
SCHEMBL3133878 0.71 HTR2C (0.38) HAO1
SCHEMBL251315 0.67 ALDH1A1 (0.41) CYP3A4HAO1
SCHEMBL930221 0.67 ESR2 (0.42) CYP3A4HAO1ESR2
SCHEMBL7741316 0.67 ESR2 (0.44) CYP3A4ESR1ESR2CYP2D6CYP2C9
SCHEMBL7741318 0.67 ESR2 (0.44) CYP3A4ESR1ESR2CYP2D6CYP2C9
SCHEMBL9252154 0.67 CYP19A1 (0.35) SLC6A3SLC6A4SLC6A2
SCHEMBL6275125 0.66 HDAC8 (0.52) HAO1ESR2
SCHEMBL15260520 0.66 HDAC8 (0.52) HAO1ESR2
SCHEMBL28584923 0.66 HDAC8 (0.52) HAO1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891314-A1 BISALKENYL DERIVATIVES, LIQUID CRYSTALLINE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORPORATION (JP) 1999-01-20 EP disclosed
WO-1997034855-A1 BISALKENYL DERIVATIVES, LIQUID CRYSTALLINE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORPORATION (JP) 1997-09-25 WO disclosed