Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 12/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 6/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008085 | 1.00 | CCR2 (0.53) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL2778896 | 1.00 | CCR2 (0.53) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL17149319 | 0.87 | CCR2 (0.40) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL17149318 | 0.87 | CCR2 (0.40) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL14040506 | 0.87 | CCR2 (0.40) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL4006271 | 0.83 | CCR2 (0.54) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL9508026 | 0.82 | HTT (0.58) | CCR2HTTRAB9A | |
| SCHEMBL8365578 | 0.82 | HTT (0.58) | CCR2HTTRAB9A | |
| SCHEMBL278259 | 0.80 | CCR2 (0.54) | CCR2HTTMMP1MMP3MMP2 | |
| SCHEMBL10824810 | 0.80 | CCR2 (0.49) | CCR2HTTMMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045378-A1 | AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |