Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353712 | 0.93 | MAPK1 (0.69) | GAAMAPK1TSHRPOLBLMNA | |
| SCHEMBL8350499 | 0.90 | GAA (0.77) | GAAMAPK1TSHRPOLBLMNA | |
| SCHEMBL6877987 | 0.85 | GAA (0.59) | GAAMAPK1POLBLMNAKMT2A | |
| SCHEMBL8353465 | 0.81 | GAA (0.54) | GAAMAPK1POLBLMNAKMT2A | |
| SCHEMBL9232215 | 0.80 | GAA (1.00) | GAAMAPK1TSHRPOLBLMNA | |
| SCHEMBL8350301 | 0.78 | ALDH1A1 (0.54) | GAAPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL6520420 | 0.77 | GAA (0.77) | GAAMAPK1TSHRPOLBLMNA | |
| SCHEMBL7503570 | 0.77 | GAA (0.77) | GAAMAPK1TSHRPOLBLMNA | |
| SCHEMBL7930533 | 0.77 | GAA (0.77) | GAAMAPK1TSHRPOLBLMNA | |
| Acetic Acid SCHEMBL8356398 | 0.76 | KMT2A (0.50) | GAAPOLBKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |