Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350499 | 0.88 | GAA (0.77) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL8353465 | 0.87 | GAA (0.54) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL8358181 | 0.85 | GAA (0.66) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL4968797 | 0.84 | SMN1; SMN2 (0.65) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL8350301 | 0.84 | ALDH1A1 (0.54) | GAAALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL8353712 | 0.83 | MAPK1 (0.69) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL6878797 | 0.80 | ALDH1A1 (0.62) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| Acetic Acid SCHEMBL8356398 | 0.78 | KMT2A (0.50) | GAAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL7419507 | 0.78 | SMN1; SMN2 (0.56) | GAAALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL15709932 | 0.77 | ALDH1A1 (0.54) | GAAALDH1A1POLBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |