⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831072 | 0.85 | — | — | |
| SCHEMBL8913647 | 0.81 | AGTR1 (0.52) | — | |
| SCHEMBL8913223 | 0.78 | AGTR1 (0.49) | — | |
| SCHEMBL8327383 | 0.77 | — | — | |
| SCHEMBL9318419 | 0.77 | AGTR1 (0.46) | — | |
| SCHEMBL5427807 | 0.76 | — | — | |
| SCHEMBL8323527 | 0.75 | — | — | |
| SCHEMBL8325457 | 0.75 | — | — | |
| SCHEMBL14409680 | 0.74 | — | — | |
| SCHEMBL8356198 | 0.74 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856337-A | 2-arylquinolines and process for producing the same | ASAHI GLASS CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| EP-0786460-A2 | 2-Arylquinolines and process for producing the same | ASAHI GLASS COMPANY LTD. (JP) | 1997-07-30 | — | — | EP | claimed |
| US-5856337-A | 2-arylquinolines and process for producing the same | ASAHI GLASS CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0786460-A2 | 2-Arylquinolines and process for producing the same | ASAHI GLASS COMPANY LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |