Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.52 |
| ▸ | GPR4 | P46093 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914997 | 0.87 | AGTR1 (0.53) | AGTR1AGTR2GPR4 | |
| L-158809 SCHEMBL683357 | 0.84 | AGTR2 (0.71) | AGTR1AGTR2GPR4 | |
| L-158809 SCHEMBL7944169 | 0.83 | AGTR2 (0.70) | AGTR1AGTR2GPR4 | |
| SCHEMBL9137241 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2GPR4 | |
| SCHEMBL9282165 | 0.82 | — | — | |
| SCHEMBL8358263 | 0.81 | — | — | |
| SCHEMBL8741166 | 0.81 | AGTR2 (0.61) | AGTR1AGTR2GPR4 | |
| SCHEMBL9135835 | 0.80 | AGTR1 (0.49) | AGTR1AGTR2GPR4 | |
| SCHEMBL8913223 | 0.80 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9426957 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0569013-B1 | Quinoline compounds as angiotensin II antagonists | GREEN CROSS CORP (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5478832-A | Angiotensin II antagonists; cardiovascular disorders | THE GREEN CROSS CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0569013-A1 | Quinoline compounds as angiotensin II antagonists | THE GREEN CROSS CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |