Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573680 | 0.90 | FPR2 (0.45) | FPR2IDO1BACE1USP7GPR119 | |
| SCHEMBL5226815 | 0.76 | CYP11B1 (0.34) | FPR2MAPTCYP11B1CYP11B2 | |
| SCHEMBL15043876 | 0.71 | NAMPT (0.53) | GPR119KDM4EPKMTP53MAPT | |
| SCHEMBL13761147 | 0.69 | KDM4E (0.51) | GPR119KDM4EPKMTP53MAPT | |
| SCHEMBL7863458 | 0.68 | FPR2 (0.43) | FPR2BACE1USP7GPR119KDM4E | |
| SCHEMBL13160667 | 0.67 | SLC2A1 (0.55) | GPR119KDM4EPKMTGFBR1 | |
| SCHEMBL3449027 | 0.66 | FPR2 (0.44) | FPR2BACE1GPR119KDM4EPKM | |
| SCHEMBL24862305 | 0.66 | GPR119 (0.55) | GPR119 | |
| SCHEMBL7971619 | 0.65 | KDM4E (0.57) | GPR119KDM4EPKMTP53MAPT | |
| SCHEMBL23531642 | 0.65 | USP7 (0.51) | IDO1BACE1USP7GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014914-A1 | ORGANIC COMPOUNDS AS AGENTS FOR THE TREATMENT OF ALDOSTERONE MEDIATED CONDITIONS | NOVARTIS AG (CH) | 2004-02-19 | — | — | WO | disclosed |