SCHEMBL8358907

SCHEMBL8358907

COCCCOc1cccc(Cl)c1NS(=O)(=O)c1nc2nc(C)cc(C)n2n1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 2/20 0.41
POLB P06746 3/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
GLA P06280 1/20 0.40
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27390670 0.95 TSHR (0.58) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL9869243 0.92 TSHR (0.60) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL8355154 0.92 TSHR (0.57) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL8359031 0.88 TSHR (0.54) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL8351627 0.88 TSHR (0.59) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL8352694 0.87 TSHR (0.53) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL8355675 0.87 TSHR (0.53) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL9869535 0.86 TSHR (0.56) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL9870388 0.85 TSHR (0.55) TSHRUSP2ALDH1A1LMNAPOLB
SCHEMBL9832562 0.85 TSHR (0.58) TSHRUSP2ALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP claimed
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP claimed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO claimed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO claimed
US-5880066-A COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE MONSANTO COMPANY (US) 1999-03-09 US disclosed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP disclosed
US-5484760-A AMIDES MONSANTO COMPANY (US) 1996-01-16 US disclosed
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP disclosed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO disclosed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO disclosed