SCHEMBL9869243

SCHEMBL9869243

COCOc1cccc(Cl)c1NS(=O)(=O)c1nc2nc(C)cc(C)n2n1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
ALDH1A1 P00352 2/20 0.49
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.43
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.41
GLA P06280 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27390670 0.92 TSHR (0.58) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL8358907 0.92 TSHR (0.57) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL8355154 0.90 TSHR (0.57) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL9869535 0.89 TSHR (0.56) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL9870388 0.88 TSHR (0.55) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL9832562 0.87 TSHR (0.58) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL8359031 0.87 TSHR (0.54) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL8351627 0.87 TSHR (0.59) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL7910513 0.86 TSHR (0.64) TSHRALDH1A1USP2LMNAPOLB
SCHEMBL8355675 0.86 TSHR (0.53) TSHRALDH1A1USP2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1063015-A Safe herbicidal sulfonamide compositions MONSANTO CO (US) 1992-07-29 CN disclosed
US-5071468-A Cereal selectivity SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1991-12-10 US disclosed