Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357186 | 0.89 | TSHR (0.55) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL8355154 | 0.88 | TSHR (0.57) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9869243 | 0.88 | TSHR (0.60) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9869535 | 0.86 | TSHR (0.56) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL8358907 | 0.85 | TSHR (0.57) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL8359031 | 0.84 | TSHR (0.54) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL8351627 | 0.84 | TSHR (0.59) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL7910513 | 0.84 | TSHR (0.64) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL8355675 | 0.84 | TSHR (0.53) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL8352694 | 0.84 | TSHR (0.53) | TSHRUSP2ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2212489-A | — | — | None | — | — | JP | disclosed |
| US-5071468-A | Cereal selectivity | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-12-10 | — | — | US | disclosed |
| JP-H02212489-A | HETEROCYCLIC TRIAZOLOPYRIMIDINE HERBICIDE | SHELL INTERNATL RES MAATSCHAPPIJ BV | 1990-08-23 | — | — | JP | disclosed |