SCHEMBL8359245

SCHEMBL8359245

CCCCc1cc(Cl)c(CCCC)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.44
TYR P14679 2/20 0.43
HPGD P15428 3/20 0.37
HTT P42858 2/20 0.37
NPC1 O15118 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX5 P09917 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TLR8 Q9NR97 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8989582 0.93 CTRC (0.44) CTRCTYRHPGDHTTMEN1
SCHEMBL16750379 0.89 TYR (0.41) CTRCTYRHPGDHTTNPC1
SCHEMBL16750381 0.89 CTRC (0.38) CTRCTYRHPGDHTTNPC1
SCHEMBL16736745 0.87 TYR (0.53) CTRCTYRHPGDHTTNPC1
SCHEMBL16736895 0.84 TYR (0.50) CTRCTYRHPGDHTTNPC1
SCHEMBL16736776 0.84 TYR (0.50) CTRCTYRHPGDHTTNPC1
SCHEMBL16736725 0.84 TYR (0.50) CTRCTYRHPGDHTTNPC1
SCHEMBL19000281 0.83 ALOX5 (0.38) CTRCTYRHTTMEN1KMT2A
SCHEMBL16750424 0.83 ALOX5 (0.42) TYRHTTMEN1KMT2ATP53
SCHEMBL27988533 0.83 ALOX5 (0.38) CTRCTYRHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5969079-A HEAT RESISTANT, HIGH STRENGTH AEROSPACE ENGINEERING THERMOPLASTICS THE BOEING COMPANY (US) 1999-10-19 US disclosed
US-5780583-A Reactive polyarylene sulfide oligomers THE BOEING COMPANY (US) 1998-07-14 US disclosed
US-5756597-A COMPOSITE; MIXTURE WITH A COMPATIBLE POLYMER THE BOEING COMPANY (US) 1998-05-26 US disclosed
US-5714566-A CONDENSING DIAMINOPHENOL WITH LINEAR OR MULTIDIMENSIONAL INTERMEDIATE TO FORM BISAMINE, CONDENSING WITH ACID HALIDE THE BOEING COMPANY (US) 1998-02-03 US disclosed
US-5610317-A CHEMICAL AND THERMAL PROPERTIES THE BOEING COMPANY (US) 1997-03-11 US disclosed
US-5256742-A Preparation of poly(arylene sulfide)s from poly(arylene sulfide disulfide) PHILLIPS PETROLEUM COMPANY (US) 1993-10-26 US disclosed
EP-0044184-A2 Blend of polyarylene sulfide and wholly aromatic polyester CELANESE CORPORATION (US) 1982-01-20 EP disclosed
US-4276397-A IMPROVED PROCESSABILITY TO FORM MOLDED ARTICLES CELANESE CORPORATION (US) 1981-06-30 US disclosed