Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360689 | 0.92 | GCGR (0.36) | ALDH1A1MAPTHPGDNPSR1CA12 | |
| SCHEMBL6732478 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL9726294 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL8692924 | 0.86 | GCGR (0.35) | KDM4EALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL9726358 | 0.84 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9189663 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL832632 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL8693608 | 0.79 | GCGR (0.34) | — | |
| SCHEMBL9726307 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL9726386 | 0.78 | LMNA (0.32) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877119-A | HERBICIDE | ROHM AND HAAS COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| US-5843867-A | Substituted pyridine compounds | ROHM AND HAAS COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5824625-A | HERBICIDES, HETEROCYCLIC GROUP(S) ATTACHED TO PYRIDINE RING | ROHM AND HAAS COMPANY | 1998-10-20 | — | — | US | disclosed |
| US-5643854-A | HERBICIDES | ROHM AND HAAS COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| US-5512536-A | HERBICIDE | ROHN AND HAAS COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| US-5391540-A | Herbicides | ROHM AND HAAS COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0573575-A1 | SUBSTITUTED PYRIDINE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| US-5228897-A | Herbicides | MONSANTO COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1992014711-A1 | SUBSTITUTED PYRIDINE COMPOUNDS | MONSANTO COMPANY (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5125956-A | Preemergence herbicides | MONSANTO COMPANY (US) | 1992-06-30 | — | — | US | disclosed |