SCHEMBL8359609

SCHEMBL8359609

CC(C)c1ccccc1-c1cccc(N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.50
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
MAP4K4 O95819 1/20 0.47
ALOX5AP P20292 1/20 0.47
FEN1 P39748 1/20 0.47
TRPA1 O75762 1/20 0.45
BRD4 O60885 1/20 0.44
ANPEP P15144 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
MAPT P10636 2/20 0.41
FFAR1 O14842 2/20 0.40
PTPN5 P54829 1/20 0.40
MECP2 P51608 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30777025 1.00 MAOA (0.50) MAOACA12CA1CA2CA9
SCHEMBL28628075 0.87 MAP4K4 (0.46) MAOACA1CA2MAP4K4ALOX5AP
SCHEMBL30865718 0.86 TRPA1 (0.51) CA12CA1CA2CA9ALOX5AP
SCHEMBL16395905 0.86 MAOA (0.47) MAOAMAP4K4ALOX5APFEN1BRD4
SCHEMBL28310912 0.81 TRPA1 (0.47) MAOACA12CA1CA2CA9
SCHEMBL16432371 0.81 MAOA (0.48) MAOACA12CA1CA2CA9
SCHEMBL21409737 0.81 MAOA (0.41) MAOAMAP4K4BRD4ANPEPADRA2A
Ethane SCHEMBL28326570 0.80 MAOA (0.62) MAOAMAP4K4BRD4MAPTMECP2
SCHEMBL2023695 0.80 MAOA (0.68) MAOACA12CA1CA2CA9
SCHEMBL29471388 0.80 MAOA (0.68) MAOACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5959068-A LIQUID POLYIMIDE BASED ON AROMATIC DIAMINE MONOMERS AND 4,4'-MONOETHYLENE TRIMELLATE AND/OR BIS/4-DICARBOXYPHENYL/-SULFONE ON A HEAT-RESISTANT FILM; ADHERING PARTS AROUND LEADFRAMES MAKING UP SEMICONDUCTOR DEVICES, E.G LEAD PINS TOMOEGAWA PAPER CO., LTD. (JP) 1999-09-28 US disclosed
US-5891540-A POLYIMIDE TOMOEGAWA PAPER CO., LTD. (JP) 1999-04-06 US disclosed
US-5866250-A POLYIMIDE TOMOEGAWA PAPER CO., LTD. (JP) 1999-02-02 US disclosed
US-5863988-A OXIDATION RESISTANT CURABLE ADHESIVE COMPRISING A DISSOLVED ACRYLONITRILE-BUTADIENE COPOLYMER, A PHENOLIC RESIN, A DIAMINE, DIMALEIMIDE COMPOUND AND/OR A POLYSILOXANE; FREE FROM GENERATING GAS, CURING AT LOW TEMPERATURE TOMOEGAWA PAPER CO., LTD. (JP) 1999-01-26 US disclosed
US-5723571-A POLYIMIDESILOXANE COPOLYMERS TOMOEGAWA PAPER CO., LTD. (JP) 1998-03-03 US disclosed