Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358829 | 0.92 | MMP13 (0.70) | MMP13HSD17B13 | |
| SCHEMBL8358832 | 0.92 | MMP13 (0.70) | MMP13NPC1 | |
| SCHEMBL8357422 | 0.89 | MMP13 (0.61) | MMP13HSD17B13CNR1 | |
| SCHEMBL5615646 | 0.86 | MMP13 (0.82) | MMP13NPC1 | |
| SCHEMBL8358426 | 0.83 | HRH4 (0.63) | MMP13CCR1 | |
| SCHEMBL14602299 | 0.81 | MMP13 (0.72) | MMP13NPC1 | |
| SCHEMBL1331786 | 0.80 | NPC1 (0.64) | NPC1 | |
| SCHEMBL6479481 | 0.79 | MMP13 (0.71) | MMP13 | |
| SCHEMBL8357429 | 0.79 | MMP13 (0.71) | MMP13CNR1 | |
| SCHEMBL8358824 | 0.78 | MMP13 (0.64) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455790-B1 | USE OF PYRIDINE-2,4-DICARBOXYLIC ACID DIAMIDES AND OF PYRIMIDINE-4,6-DICARBOXYLIC ACID DIAMIDES FOR SELECTIVE COLLAGENASE INHIBITION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-03-26 | — | — | EP | disclosed |
| WO-2003049738-A1 | USE OF PYRIDINE-2,4-DICARBOXYLIC ACID DIAMIDES AND OF PYRIMIDINE-4,6-DICARBOXYLIC ACID DIAMIDES FOR SELECTIVE COLLAGENASE INHIBITION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-06-19 | — | — | WO | disclosed |